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サイクリックヌクレオチドフォスフォジエステラーゼ

環状ヌクレオチドのリン酸ジエステル結合を切断する酵素。

PDB entries

PDB image
1RO6 - Hydrolase
Crystal Structure Of Pde4b2b Complexed With Rolipram (R & S)
リガンド:AS|MN|ROL|ZN
PDB image
1ROR - Hydrolase
Crystal Structures Of The Catalytic Domain Of Phosphodiesterase 4b2b Complexed With Amp
リガンド:AMP|ZN
PDB image
1RO9 - Hydrolase
Crystal Structures Of The Catalytic Domain Of Phosphodiesterase 4b2b Complexed With 8-Br-Amp
リガンド:8BR|ZN

References

Assignment of the 1H, 13C and 15N resonances of the catalytic domain of the rat 2',3'-cyclic nucleotide 3'-phosphodiesterase.
Kozlov G, Lee J, Gravel M, Ekiel I, Braun PE, Gehring K
J Biomol NMR22p99-100(2002 Jan)
Crystal structures of the catalytic domain of phosphodiesterase 4B complexed with AMP, 8-Br-AMP, and rolipram.
Xu RX, Rocque WJ, Lambert MH, Vanderwall DE, Luther MA, Nolte RT
J Mol Biol337p355-65(2004 Mar 19)

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