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脂肪酸合成酵素

脂肪酸合成酵素は、細胞膜の形成やエネルギーの貯蔵など生命活動には必須の脂肪酸を合成する酵素である。この酵素複合体は、アシル基の転移と還元を繰り返していくことで、炭素鎖を延長していく。

PDB image
2CF2 - Transferase
Architecture Of Mammalian Fatty Acid Synthase
PDB image
2UVB - Transferase
Crystal Structure Of Fatty Acid Synthase Complexed With Nadp+ From Thermomyces Lanuginosus At 3.1 Angstrom Resolution. This File Contains The Alpha Subunits Of The Fatty Acid Synthase. The Entire Crystal Structure Consists Of One Heterododecameric Fatty Acid Synthase And Is Described In Remark 400
リガンド:NAP

References

  1. The structural biology of type II fatty acid biosynthesis.
    White SW, Zheng J, Zhang YM, Rock
    Annu Rev Biochem74p791-831(2005)

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